Intranuclear Hemoglobin in Erythroblasts of f3-Thalassemia

The amount and distribution of intranuclear suggested the presence of intranuclear hehemoglobin in erythroblasts of normal submoglobin precipitation in some cells. jects and patients with homozygous Similar characteristic absorption peaks of thalassemia were studied by microspecdenatured ferric hemoglobin were recorded trophotometric methods. The mean intranuover large inclusions of the cytoplasm and clear hemoglobin content of the mature small intranuclear precipitates. Intranuclear erythroblasts represented 33%-40% of the inclusion bodies may be responsible for the total hemoglobin content both in normal disturbance of erythroblast proliferation in and thalassemic cells. Distinct absorption thalassemia, thus explaining in part the peaks in transmission scanning lines ineffective erythropoiesis occurring in this recorded over thalassemic erythroblasts disease.